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Without the bacteria that live in our intestines, a drug used against rheumatoid arthritis and inflammatory bowel disease wouldn’t work. The microbes produce an enzyme that cleaves and activates a key...

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New genetic links for Crohn’s, colitis

Crohn’s disease (CD) and ulcerative colitis (UC) — inflammatory diseases of the gastrointestinal tract — have puzzled the scientific community for decades. Ten years ago, researchers recognized that...

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Imbalance in microbial population found in Crohn’s patients

A multi-institutional study led by investigators from Harvard-affiliated Massachusetts General Hospital (MGH) and the Broad Institute of Harvard and MIT reports that newly diagnosed Crohn’s disease...

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Meditation may relieve IBS and IBD

A pilot study has found that participating in a nine-week training program including elicitation of the relaxation response had a significant impact on clinical symptoms of the gastrointestinal...

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Polygenic risk scoring flags likelihood of developing common diseases

A research team at the Broad Institute of MIT and Harvard, Massachusetts General Hospital (MGH), and Harvard Medical School (HMS) reports a new kind of genome analysis that could identify large...

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New findings from Harvard reveal how IBD disrupts gut bacteria

A new study led by researchers from Harvard T.H. Chan School of Public Health and the Broad Institute of MIT and Harvard is the first to have observed the complex set of chemical and molecular events...

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A probiotic therapy for patients with inflammatory bowel disease

About 1.6 million people in the U.S.  have an incurable inflammatory bowel disease (IBD) such as Crohn’s or ulcerative colitis, and 70,000 new cases are diagnosed each year. IBD patients suffer from...

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Study probes caffeine’s role in gut health, IBD

The gut is home to a cast of microbes that influence health and disease. Some types of microorganisms are thought to contribute to the development of inflammatory conditions, such as inflammatory bowel...

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